Abuse of any drug legal or not is extremely dangerous. There are many adverse effects from different drugs. It is essential to treat with first aid and get professional medical help as soon as possible. Accidental and intentional overdosing is the most common poisoning worldwide. Taking more pain medication does NOT ease pain faster. But rather excessive amounts of drugs such as Acetaminophen (Tylenol) can cause liver toxicity, and liver failure, while excessive amounts of Aspirin can cause internal bleeding, and kidney failure. Death can occur if medical treatment is not sought immediately.